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Structural and oxidative investigation of a recombinant high-yielding fetal hemoglobin mutant

Human fetal hemoglobin (HbF) is an attractive starting protein for developing an effective agent for oxygen therapeutics applications. This requires that HbF can be produced in heterologous systems at high levels and in a homogeneous form. The introduction of negative charges on the surface of the α...

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Detalles Bibliográficos
Autores principales: Kettisen, Karin, Nyblom, Maria, Smeds, Emanuel, Fago, Angela, Bülow, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060959/
https://www.ncbi.nlm.nih.gov/pubmed/37006610
http://dx.doi.org/10.3389/fmolb.2023.1133985