Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression

Synthetic cannabinoids have exhibited unpredictable abuse liabilities, especially self-administration (SA) responses in normal rodent models, despite seemingly inducing addiction-like effects in humans. Thus, an efficient pre-clinical model must be developed to determine cannabinoid abuse potential...

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Detalles Bibliográficos
Autores principales: Sayson, Leandro Val, Ortiz, Darlene Mae, Lee, Hyun Jun, Kim, Mikyung, Custodio, Raly James Perez, Yun, Jaesuk, Lee, Chae Hyeon, Lee, Yong Sup, Cha, Hye Jin, Cheong, Jae Hoon, Kim, Hee Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060981/
https://www.ncbi.nlm.nih.gov/pubmed/37007015
http://dx.doi.org/10.3389/fphar.2023.1135929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060981/
https://www.ncbi.nlm.nih.gov/pubmed/37007015
http://dx.doi.org/10.3389/fphar.2023.1135929

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