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Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration

Low back pain (LBP) is a prevalent health problem worldwide that affects over 80% of adults during their lifetime. Intervertebral disc degeneration (IDD) is a well-recognized leading cause of LBP. IDD is classified into five grades according to the Pfirrmann classification system. The purpose of thi...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Lu, Yang, Zhou, Hang, Jiang, Hai-Tao, Chu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061025/
https://www.ncbi.nlm.nih.gov/pubmed/37009470
http://dx.doi.org/10.3389/fcell.2023.1136777