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Characterization of ligand-induced thermal stability of the human organic cation transporter 2 (OCT2)

Introduction: The human organic cation transporter 2 (OCT2) is involved in the transport of endogenous quaternary amines and positively charged drugs across the basolateral membrane of proximal tubular cells. In the absence of a structure, the progress in unraveling the molecular basis of OCT2 subst...

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Detalles Bibliográficos
Autores principales: Maane, Max, Xiu, Fangrui, Bellstedt, Peter, Kullak-Ublick, Gerd A., Visentin, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061065/
https://www.ncbi.nlm.nih.gov/pubmed/37007010
http://dx.doi.org/10.3389/fphar.2023.1154213