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Single‐cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers

An immunosuppressive state is regulated by various factors in the tumor microenvironment (TME), including, but not limited to, metabolic plasticity of immunosuppressive cells and cytokines secreted by these cells. We used single‐cell RNA‐sequencing (scRNA‐seq) data and applied single‐cell flux estim...

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Detalles Bibliográficos
Autores principales: Wei, Jinfen, Yu, Wenqi, Chen, Juanzhi, Huang, Guanda, Zhang, Lingjie, Chen, Zixi, Hu, Meiling, Gong, Xiaocheng, Du, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061288/
https://www.ncbi.nlm.nih.gov/pubmed/36587392
http://dx.doi.org/10.1002/1878-0261.13373