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Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios

IMPORTANCE: Chronic kidney disease (CKD) has been associated with increased plasma concentrations of phosphorylated tau (p-tau) 217 and p-tau181, which potentially decreases their usefulness in the diagnostic workup of Alzheimer disease (AD). OBJECTIVE: To investigate associations of CKD with plasma...

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Detalles Bibliográficos
Autores principales: Janelidze, Shorena, Barthélemy, Nicolas R., He, Yingxin, Bateman, Randall J., Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061310/
https://www.ncbi.nlm.nih.gov/pubmed/36987840
http://dx.doi.org/10.1001/jamaneurol.2023.0199