Real-Time Library Search Increases Cross-Link Identification Depth across All Levels of Sample Complexity

[Image: see text] Cross-linking mass spectrometry (XL-MS) is a universal tool for probing structural dynamics and protein–protein interactions in vitro and in vivo. Although cross-linked peptides are naturally less abundant than their unlinked counterparts, recent experimental advances improved cros...

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Detalles Bibliográficos
Autores principales: Ruwolt, Max, He, Yi, Borges Lima, Diogo, Barshop, William, Broichhagen, Johannes, Huguet, Romain, Viner, Rosa, Liu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061366/
https://www.ncbi.nlm.nih.gov/pubmed/36926872
http://dx.doi.org/10.1021/acs.analchem.2c05141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061366/
https://www.ncbi.nlm.nih.gov/pubmed/36926872
http://dx.doi.org/10.1021/acs.analchem.2c05141

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