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Inhibition of NF-κB ameliorates aberrant retinal glia activation and inflammatory responses in streptozotocin-induced diabetic rats

BACKGROUND: To determine the anti-inflammatory effects of IMD-0354, a specific NF-κB blocker, on glial cells in rats with streptozotocin (STZ)-induced diabetic retinopathy (DR). METHODS: The following four groups of rats were used: control, control + IMD-0354, STZ, and STZ + IMD-0354. After six week...

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Detalles Bibliográficos
Autores principales: Ding, Xinyi, Sun, Zhongcui, Guo, Yue, Tang, Wenyi, Shu, Qinmeng, Xu, Gezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061458/
https://www.ncbi.nlm.nih.gov/pubmed/37007562
http://dx.doi.org/10.21037/atm-22-2204