Oncolytic adenovirus-mediated dual knockdown of survivin and OCT4 improves therapeutic efficacy in esophageal cancer

BACKGROUND: Survivin and octamer-binding transcription factor 4 (OCT4) are reportedly up-regulated in esophageal cancer (EC) and have been correlated with high tumor proliferative activity and poor prognosis. Oncolytic viruses encoding specific transgenes have been considered as therapeutic methods...

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Detalles Bibliográficos
Autores principales: Li, Chunguang, Zhu, Maoling, Lu, Qijue, Yu, Boyao, Yang, Yang, Li, Bin, Peng, Zhangxiao, Li, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061493/
https://www.ncbi.nlm.nih.gov/pubmed/37007541
http://dx.doi.org/10.21037/atm-22-4499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061493/
https://www.ncbi.nlm.nih.gov/pubmed/37007541
http://dx.doi.org/10.21037/atm-22-4499

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