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Oncolytic adenovirus-mediated dual knockdown of survivin and OCT4 improves therapeutic efficacy in esophageal cancer
BACKGROUND: Survivin and octamer-binding transcription factor 4 (OCT4) are reportedly up-regulated in esophageal cancer (EC) and have been correlated with high tumor proliferative activity and poor prognosis. Oncolytic viruses encoding specific transgenes have been considered as therapeutic methods...
Autores principales: | Li, Chunguang, Zhu, Maoling, Lu, Qijue, Yu, Boyao, Yang, Yang, Li, Bin, Peng, Zhangxiao, Li, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061493/ https://www.ncbi.nlm.nih.gov/pubmed/37007541 http://dx.doi.org/10.21037/atm-22-4499 |
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