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Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation

Intercellular communication between axons and Schwann cells is critical for attaining the complex morphological steps necessary for axon maturation. In the early onset motor neuron disease spinal muscular atrophy (SMA), many motor axons are not ensheathed by Schwann cells nor grow sufficiently in ra...

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Detalles Bibliográficos
Autores principales: Kong, Lingling, Hassinan, Cera W., Gerstner, Florian, Buettner, Jannik M., Petigrow, Jeffrey B., Valdivia, David O., Chan-Cortés, Michelle H., Mistri, Amy, Cao, Annie, McGaugh, Scott Alan, Denton, Madeline, Brown, Stephen, Ross, Joshua, Schwab, Markus H., Simon, Christian M., Sumner, Charlotte J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061791/
https://www.ncbi.nlm.nih.gov/pubmed/36997967
http://dx.doi.org/10.1186/s40478-023-01551-8