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Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination

BACKGROUND: Although metastasis is the foremost cause of cancer-related death, a specialized mechanism that reprograms anchorage dependency of solid tumor cells into circulating tumor cells (CTCs) during metastatic dissemination remains a critical area of challenge. METHODS: We analyzed blood cell-s...

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Detalles Bibliográficos
Autores principales: Huh, Hyunbin D., Sub, Yujin, Oh, Jongwook, Kim, Ye Eun, Lee, Ju Young, Kim, Hwa-Ryeon, Lee, Soyeon, Lee, Hannah, Pak, Sehyung, Amos, Sebastian E., Vahala, Danielle, Park, Jae Hyung, Shin, Ji Eun, Park, So Yeon, Kim, Han Sang, Roh, Young Hoon, Lee, Han-Woong, Guan, Kun-Liang, Choi, Yu Suk, Jeong, Joon, Choi, Junjeong, Roe, Jae-Seok, Gee, Heon Yung, Park, Hyun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061822/
https://www.ncbi.nlm.nih.gov/pubmed/36991428
http://dx.doi.org/10.1186/s12943-023-01753-7