H3K27me3-H3K4me1 transition at bivalent promoters instructs lineage specification in development

BACKGROUND: Bivalent genes, of which promoters are marked by both H3K4me3 (trimethylation of histone H3 on lysine 4) and H3K27me3 (trimethylation of histone H3 on lysine 27), play critical roles in development and tumorigenesis. Monomethylation on lysine 4 of histone H3 (H3K4me1) is commonly associa...

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Detalles Bibliográficos
Autores principales: Yu, Yue, Li, Xinjie, Jiao, Rui, Lu, Yang, Jiang, Xuan, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061859/
https://www.ncbi.nlm.nih.gov/pubmed/36991495
http://dx.doi.org/10.1186/s13578-023-01017-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061859/
https://www.ncbi.nlm.nih.gov/pubmed/36991495
http://dx.doi.org/10.1186/s13578-023-01017-3

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