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H3K27me3-H3K4me1 transition at bivalent promoters instructs lineage specification in development
BACKGROUND: Bivalent genes, of which promoters are marked by both H3K4me3 (trimethylation of histone H3 on lysine 4) and H3K27me3 (trimethylation of histone H3 on lysine 27), play critical roles in development and tumorigenesis. Monomethylation on lysine 4 of histone H3 (H3K4me1) is commonly associa...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061859/ https://www.ncbi.nlm.nih.gov/pubmed/36991495 http://dx.doi.org/10.1186/s13578-023-01017-3 |