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circACTR2 attenuates gemcitabine chemoresiatance in pancreatic cancer through PTEN mediated PI3K/AKT signaling pathway

BACKGROUND: Recently, accumulating studies have unveiled that circRNAs exert critical function in a variety of tumor biological processes including chemoresistance. Our previous study has found circACTR2 is significantly down-regulated in acquired gemcitabine (GEM)- resistant pancreatic cancer (PC)...

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Detalles Bibliográficos
Autores principales: Xu, Chao, Ye, Qinwen, Ye, Chao, Liu, Shaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061898/
https://www.ncbi.nlm.nih.gov/pubmed/36991449
http://dx.doi.org/10.1186/s13062-023-00368-8