Cargando…

Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures

Messenger RNA (mRNA) lipid nanoparticles (LNPs) have emerged at the forefront during the COVID-19 vaccination campaign. Despite their tremendous success, mRNA vaccines currently require storage at deep freeze temperatures which complicates their storage and distribution, and ultimately leads to lowe...

Descripción completa

Detalles Bibliográficos
Autores principales: Meulewaeter, Sofie, Nuytten, Gust, Cheng, Miffy H.Y., De Smedt, Stefaan C., Cullis, Pieter R., De Beer, Thomas, Lentacker, Ine, Verbeke, Rein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062427/
https://www.ncbi.nlm.nih.gov/pubmed/36958400
http://dx.doi.org/10.1016/j.jconrel.2023.03.039