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Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures
Messenger RNA (mRNA) lipid nanoparticles (LNPs) have emerged at the forefront during the COVID-19 vaccination campaign. Despite their tremendous success, mRNA vaccines currently require storage at deep freeze temperatures which complicates their storage and distribution, and ultimately leads to lowe...
Autores principales: | Meulewaeter, Sofie, Nuytten, Gust, Cheng, Miffy H.Y., De Smedt, Stefaan C., Cullis, Pieter R., De Beer, Thomas, Lentacker, Ine, Verbeke, Rein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062427/ https://www.ncbi.nlm.nih.gov/pubmed/36958400 http://dx.doi.org/10.1016/j.jconrel.2023.03.039 |
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