The immune checkpoint molecule, VTCN1/B7-H4, guides differentiation and suppresses proinflammatory responses and MHC class I expression in an embryonic stem cell-derived model of human trophoblast

The placenta acts as a protective barrier to pathogens and other harmful substances present in the maternal circulation throughout pregnancy. Disruption of placental development can lead to complications of pregnancy such as preeclampsia, intrauterine growth retardation and preterm birth. In previou...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Tian, Yuchen, Qu, Ying, Williams, Madyson, Yuan, Ye, Karvas, Rowan M., Sheridan, Megan A., Schulz, Laura C., Ezashi, Toshihiko, Roberts, Michael R., Schust, Danny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062451/
https://www.ncbi.nlm.nih.gov/pubmed/37008954
http://dx.doi.org/10.3389/fendo.2023.1069395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062451/
https://www.ncbi.nlm.nih.gov/pubmed/37008954
http://dx.doi.org/10.3389/fendo.2023.1069395

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