Identification of cancer-related genes FGFR2 and CEBPB in choledochal cyst via RNA sequencing of patient-derived liver organoids

BACKGROUND: Choledochal cysts (CC) are congenital bile duct anomalies with 6–30% risk for developing bile duct cancer. However, the molecular mechanisms underlying cancer risk of CC are unknown. We sought to identify the gene expression changes underlying the cancer risk of CC patients. METHODS: Liv...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Yongqin, Lui, Vincent Chi Hang, Babu, Rosana Ottakandathil, Wu, Zhongluan, Wu, Weifang, Chung, Patrick Ho Yu, Wong, Kenneth Kak Yuen, Wang, Bin, Tam, Paul Kwong Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062558/
https://www.ncbi.nlm.nih.gov/pubmed/36996081
http://dx.doi.org/10.1371/journal.pone.0283737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062558/
https://www.ncbi.nlm.nih.gov/pubmed/36996081
http://dx.doi.org/10.1371/journal.pone.0283737

Ejemplares similares