A snapshot on HIV-1 evolution through the identification of phylogenetic-specific properties of HIV-1 integrases M/O

Transmissions of simian viruses to humans has originated the different groups of HIV-1. We recently identified a functional motif (CLA), in the C-terminal domain of the integrase, essential for integration in HIV-1 group M. Here, we found that the motif is instead dispensable in group O isolates, be...

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Detalles Bibliográficos
Autores principales: Toccafondi, Elenia, Kanja, Marine, Winter, Flore, Lener, Daniela, Negroni, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062586/
https://www.ncbi.nlm.nih.gov/pubmed/36996029
http://dx.doi.org/10.1371/journal.ppat.1011207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062586/
https://www.ncbi.nlm.nih.gov/pubmed/36996029
http://dx.doi.org/10.1371/journal.ppat.1011207

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