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A snapshot on HIV-1 evolution through the identification of phylogenetic-specific properties of HIV-1 integrases M/O
Transmissions of simian viruses to humans has originated the different groups of HIV-1. We recently identified a functional motif (CLA), in the C-terminal domain of the integrase, essential for integration in HIV-1 group M. Here, we found that the motif is instead dispensable in group O isolates, be...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062586/ https://www.ncbi.nlm.nih.gov/pubmed/36996029 http://dx.doi.org/10.1371/journal.ppat.1011207 |