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Necrotic cardiac myocytes skew macrophage polarization towards a classically activated phenotype

Necrotic and dying cells release damage-associated molecular patterns (DAMPs) that can initiate sterile inflammatory responses in the heart. Although macrophages are essential for myocardial repair and regeneration, the effect of DAMPs on macrophage activation remains unclear. To address this gap in...

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Detalles Bibliográficos
Autores principales: Jiang, Wenlong, Adamo, Luigi, Lim, Kenji, Matkovich, Scot J, Evans, Sarah, Rocha-Resende, Cibele, Mann, Douglas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062615/
https://www.ncbi.nlm.nih.gov/pubmed/36996254
http://dx.doi.org/10.1371/journal.pone.0282921