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Necrotic cardiac myocytes skew macrophage polarization towards a classically activated phenotype
Necrotic and dying cells release damage-associated molecular patterns (DAMPs) that can initiate sterile inflammatory responses in the heart. Although macrophages are essential for myocardial repair and regeneration, the effect of DAMPs on macrophage activation remains unclear. To address this gap in...
Autores principales: | Jiang, Wenlong, Adamo, Luigi, Lim, Kenji, Matkovich, Scot J, Evans, Sarah, Rocha-Resende, Cibele, Mann, Douglas L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062615/ https://www.ncbi.nlm.nih.gov/pubmed/36996254 http://dx.doi.org/10.1371/journal.pone.0282921 |
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