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Fluorescence based HTS-compatible ligand binding assays for dopamine D(3) receptors in baculovirus preparations and live cells

Dopamine receptors are G-protein-coupled receptors that are connected to severe neurological disorders. The development of new ligands targeting these receptors enables gaining a deeper insight into the receptor functioning, including binding mechanisms, kinetics and oligomerization. Novel fluoresce...

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Detalles Bibliográficos
Autores principales: Tahk, Maris-Johanna, Laasfeld, Tõnis, Meriste, Elo, Brea, Jose, Loza, Maria Isabel, Majellaro, Maria, Contino, Marialessandra, Sotelo, Eddy, Rinken, Ago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062709/
https://www.ncbi.nlm.nih.gov/pubmed/37006609
http://dx.doi.org/10.3389/fmolb.2023.1119157