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Synthesis, antimycobacterial screening, molecular docking, ADMET prediction and pharmacological evaluation on novel pyran-4-one bearing hydrazone, triazole and isoxazole moieties: Potential inhibitors of SARS CoV-2

The respiratory infection tuberculosis is caused by the bacteria Mycobacterium tuberculosis and its unrelenting spread caused millions of deaths around the world. Hence, it is needed to explore potential and less toxic anti-tubercular drugs. In the present work, we report the synthesis and antituber...

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Detalles Bibliográficos
Autores principales: Ravisankar, N., Sarathi, N., Maruthavanan, T., Ramasundaram, Subramaniyan, Ramesh, M., Sankar, C., Umamatheswari, S., Kanthimathi, G., Oh, Tae Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062711/
https://www.ncbi.nlm.nih.gov/pubmed/37041803
http://dx.doi.org/10.1016/j.molstruc.2023.135461