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A Vaccinia-based system for directed evolution of GPCRs in mammalian cells
Directed evolution in bacterial or yeast display systems has been successfully used to improve stability and expression of G protein-coupled receptors for structural and biophysical studies. Yet, several receptors cannot be tackled in microbial systems due to their complex molecular composition or u...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063554/ https://www.ncbi.nlm.nih.gov/pubmed/36997531 http://dx.doi.org/10.1038/s41467-023-37191-8 |