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Primitive haematopoiesis in the human placenta gives rise to macrophages with epigenetically silenced HLA-DR

The earliest macrophages are generated during embryonic development from erythro-myeloid progenitors (EMPs) via primitive haematopoiesis. Although this process is thought to be spatially restricted to the yolk sac in the mouse, in humans, it remains poorly understood. Human foetal placental macropha...

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Detalles Bibliográficos
Autores principales: Thomas, Jake R., Appios, Anna, Calderbank, Emily F., Yoshida, Nagisa, Zhao, Xiaohui, Hamilton, Russell S., Moffett, Ashley, Sharkey, Andrew, Laurenti, Elisa, Hanna, Courtney W., McGovern, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063560/
https://www.ncbi.nlm.nih.gov/pubmed/36997537
http://dx.doi.org/10.1038/s41467-023-37383-2