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Primitive haematopoiesis in the human placenta gives rise to macrophages with epigenetically silenced HLA-DR
The earliest macrophages are generated during embryonic development from erythro-myeloid progenitors (EMPs) via primitive haematopoiesis. Although this process is thought to be spatially restricted to the yolk sac in the mouse, in humans, it remains poorly understood. Human foetal placental macropha...
Autores principales: | Thomas, Jake R., Appios, Anna, Calderbank, Emily F., Yoshida, Nagisa, Zhao, Xiaohui, Hamilton, Russell S., Moffett, Ashley, Sharkey, Andrew, Laurenti, Elisa, Hanna, Courtney W., McGovern, Naomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063560/ https://www.ncbi.nlm.nih.gov/pubmed/36997537 http://dx.doi.org/10.1038/s41467-023-37383-2 |
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