NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells

Anti-neoplastic effect of DNA cross-linking agents such as cisplatin, mitomycin C, and psoralen is attributed to their ability to induce DNA interstrand cross-links (ICLs), which block replication, transcription, and linear repair pathways by preventing DNA strand separation and trigger apoptosis. I...

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Detalles Bibliográficos
Autores principales: Aliyaskarova, Umit, Baiken, Yeldar, Renaud, Flore, Couve, Sophie, Kisselev, Alexei F., Saparbaev, Murat, Groisman, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063580/
https://www.ncbi.nlm.nih.gov/pubmed/36997601
http://dx.doi.org/10.1038/s41598-023-32186-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063580/
https://www.ncbi.nlm.nih.gov/pubmed/36997601
http://dx.doi.org/10.1038/s41598-023-32186-3

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