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NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells
Anti-neoplastic effect of DNA cross-linking agents such as cisplatin, mitomycin C, and psoralen is attributed to their ability to induce DNA interstrand cross-links (ICLs), which block replication, transcription, and linear repair pathways by preventing DNA strand separation and trigger apoptosis. I...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063580/ https://www.ncbi.nlm.nih.gov/pubmed/36997601 http://dx.doi.org/10.1038/s41598-023-32186-3 |