Integration of epigenetic and genetic profiles identifies multiple sclerosis disease-critical cell types and genes

Genome-wide association studies (GWAS) successfully identified multiple sclerosis (MS) susceptibility variants. Despite this notable progress, understanding the biological context of these associations remains challenging, due in part to the complexity of linking GWAS results to causative genes and...

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Detalles Bibliográficos
Autores principales: Ma, Qin, Shams, Hengameh, Didonna, Alessandro, Baranzini, Sergio E., Cree, Bruce A. C., Hauser, Stephen L., Henry, Roland G., Oksenberg, Jorge R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063586/
https://www.ncbi.nlm.nih.gov/pubmed/36997638
http://dx.doi.org/10.1038/s42003-023-04713-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063586/
https://www.ncbi.nlm.nih.gov/pubmed/36997638
http://dx.doi.org/10.1038/s42003-023-04713-5

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