Unravelling the clinicopathological and functional significance of replication protein A (RPA) heterotrimeric complex in breast cancers

Replication Protein A (RPA), a heterotrimeric complex consisting of RPA1, 2, and 3 subunits, is a single-stranded DNA (ssDNA)-binding protein that is critically involved in replication, checkpoint regulation and DNA repair. Here we have evaluated RPA in 776 pure ductal carcinomas in situ (DCIS), 239...

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Detalles Bibliográficos
Autores principales: Algethami, Mashael, Toss, Michael S., Woodcock, Corinne L., Jaipal, Chandar, Brownlie, Juliette, Shoqafi, Ahmed, Alblihy, Adel, Mesquita, Katia A., Green, Andrew R., Mongan, Nigel P., Jeyapalan, Jennie N., Rakha, Emad A., Madhusudan, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063624/
https://www.ncbi.nlm.nih.gov/pubmed/36997566
http://dx.doi.org/10.1038/s41523-023-00524-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063624/
https://www.ncbi.nlm.nih.gov/pubmed/36997566
http://dx.doi.org/10.1038/s41523-023-00524-3

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