Hyperpolarized δ-[1- (13)C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma

TERT promoter mutations are a hallmark of glioblastoma (GBM). Accordingly, TERT and GABPB1, a subunit of the upstream mutant TERT promoter transcription factor GABP, are being considered as promising therapeutic targets in GBM. We recently reported that the expression of TERT or GABP1 modulates flux...

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Detalles Bibliográficos
Autores principales: Minami, Noriaki, Hong, Donghyun, Taglang, Celine, Batsios, Georgios, Gillespie, Anne Marie, Viswanath, Pavithra, Stevers, Nicholas, Barger, Carter J., Costello, Joseph F., Ronen, Sabrina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063634/
https://www.ncbi.nlm.nih.gov/pubmed/36997627
http://dx.doi.org/10.1038/s41598-023-32463-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063634/
https://www.ncbi.nlm.nih.gov/pubmed/36997627
http://dx.doi.org/10.1038/s41598-023-32463-1

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