Epigenetic clocks suggest accelerated aging in patients with isolated REM Sleep Behavior Disorder

Isolated REM Sleep Behavior Disorder (iRBD) is the strongest prodromal marker for α-synucleinopathies. Overt α-synucleinopathies and aging share several mechanisms, but this relationship has been poorly investigated in prodromal phases. Using DNA methylation-based epigenetic clocks, we measured biol...

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Detalles Bibliográficos
Autores principales: Baldelli, Luca, Pirazzini, Chiara, Sambati, Luisa, Ravaioli, Francesco, Gentilini, Davide, Calandra-Buonaura, Giovanna, Guaraldi, Pietro, Franceschi, Claudio, Cortelli, Pietro, Garagnani, Paolo, Bacalini, Maria Giulia, Provini, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063653/
https://www.ncbi.nlm.nih.gov/pubmed/36997543
http://dx.doi.org/10.1038/s41531-023-00492-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063653/
https://www.ncbi.nlm.nih.gov/pubmed/36997543
http://dx.doi.org/10.1038/s41531-023-00492-2

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