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DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia

Non-obstructive azoospermia, the absence of sperm in the ejaculate due to disturbed spermatogenesis, represents the most severe form of male infertility. De novo microdeletions of the Y-chromosomal AZFa region are one of few well-established genetic causes for NOA and are routinely analysed in the d...

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Detalles Bibliográficos
Autores principales: Dicke, Ann-Kristin, Pilatz, Adrian, Wyrwoll, Margot J., Punab, Margus, Ruckert, Christian, Nagirnaja, Liina, Aston, Kenneth I., Conrad, Donald F., Di Persio, Sara, Neuhaus, Nina, Fietz, Daniela, Laan, Maris, Stallmeyer, Birgit, Tüttelmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063662/
https://www.ncbi.nlm.nih.gov/pubmed/36997603
http://dx.doi.org/10.1038/s42003-023-04714-4