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The in vivo measurement of replication fork velocity and pausing by lag-time analysis

An important step towards understanding the mechanistic basis of the central dogma is the quantitative characterization of the dynamics of nucleic-acid-bound molecular motors in the context of the living cell. To capture these dynamics, we develop lag-time analysis, a method for measuring in vivo dy...

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Detalles Bibliográficos
Autores principales: Huang, Dean, Johnson, Anna E., Sim, Brandon S., Lo, Teresa W., Merrikh, Houra, Wiggins, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063678/
https://www.ncbi.nlm.nih.gov/pubmed/36997519
http://dx.doi.org/10.1038/s41467-023-37456-2