Deficient leptin receptor signaling in T cells of human SLE

BACKGROUND: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease mainly mediated by IgG autoantibody. While follicular helper T (Tfh) cells are crucial for supporting IgG autoantibody generation in human SLE, underlying mechanisms for Tfh cell mal-differentiation remain unclear. MET...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Zheng, Ming, Jia, Li, Wang, Mingyuan, Tang, Longhai, Wen, Zhenke, Zhang, Miaojia, Yuan, Fenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063787/
https://www.ncbi.nlm.nih.gov/pubmed/37006245
http://dx.doi.org/10.3389/fimmu.2023.1157731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063787/
https://www.ncbi.nlm.nih.gov/pubmed/37006245
http://dx.doi.org/10.3389/fimmu.2023.1157731

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