Cargando…

Deficient leptin receptor signaling in T cells of human SLE

BACKGROUND: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease mainly mediated by IgG autoantibody. While follicular helper T (Tfh) cells are crucial for supporting IgG autoantibody generation in human SLE, underlying mechanisms for Tfh cell mal-differentiation remain unclear. MET...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ting, Zheng, Ming, Jia, Li, Wang, Mingyuan, Tang, Longhai, Wen, Zhenke, Zhang, Miaojia, Yuan, Fenghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063787/ https://www.ncbi.nlm.nih.gov/pubmed/37006245 http://dx.doi.org/10.3389/fimmu.2023.1157731

Ejemplares similares

Clearance Deficiency and Cell Death Pathways: A Model for the Pathogenesis of SLE
por: Mahajan, Aparna, et al.
Publicado: (2016)

Editorial: Mechanisms by Which SLE-Associated Genetic Variants Contribute to SLE Pathogenesis
por: Crispín, José C., et al.
Publicado: (2019)

C-Reactive Protein (CRP) and Leptin Receptor in Obesity: Binding of Monomeric CRP to Leptin Receptor
por: Sudhakar, Manu, et al.
Publicado: (2018)

IFNα Inducible Models of Murine SLE
por: Liu, Zheng, et al.
Publicado: (2013)

PRDX6AS1 gene polymorphisms and SLE susceptibility in Chinese populations
por: Zhang, Xiao-Xue, et al.
Publicado: (2022)

Defects in Germinal Center Selection in SLE
por: Woods, Megan, et al.
Publicado: (2015)

SLE: Novel Postulates for Therapeutic Options
por: Hosszu, Kinga K., et al.
Publicado: (2020)

IFN-γ, should not be ignored in SLE
por: Liu, Wenping, et al.
Publicado: (2022)

Duration biased distribution of clinical and immunological phenotypes in active SLE
por: Yan, Qingran, et al.
Publicado: (2022)

Activation of the Interferon Pathway is Dependent Upon Autoantibodies in African-American SLE Patients, but Not in European-American SLE Patients
por: Ko, Kichul, et al.
Publicado: (2013)

Assessing the Function of the ZFP90 Variant rs1170426 in SLE and the Association Between SLE Drug Target and Susceptibility Genes
por: Zhu, Tingting, et al.
Publicado: (2021)

Corrigendum: Assessing the Function of the ZFP90 Variant rs1170426 in SLE and the Association Between SLE Drug Target and Susceptibility Genes
por: Zhu, Tingting, et al.
Publicado: (2022)

Characterization of Leptin Receptor(+) Stromal Cells in Lymph Node
por: Jiang, Liwei, et al.
Publicado: (2022)

Leptin deficiency in CD8(+) T cells ameliorates non-segmental vitiligo by reducing interferon-γ and Granzyme B
por: Wu, Meiyu, et al.
Publicado: (2023)

Leptin- and Leptin Receptor-Deficient Rodent Models: Relevance for Human Type 2 Diabetes
por: Wang, Bingxuan, et al.
Publicado: (2014)

SLE: Another Autoimmune Disorder Influenced by Microbes and Diet?
por: Mu, Qinghui, et al.
Publicado: (2015)

Ex-TFRs: A Missing Piece of the SLE Puzzle?
por: Wei, Xundong, et al.
Publicado: (2021)

Interferon Genes Are Influenced by 17β-Estradiol in SLE
por: Singh, Ram P., et al.
Publicado: (2021)

BTLA Expression and Function Are Impaired on SLE B Cells
por: Wiedemann, Annika, et al.
Publicado: (2021)

A High Prevalence of Anti-EBNA1 Heteroantibodies in Systemic Lupus Erythematosus (SLE) Supports Anti-EBNA1 as an Origin for SLE Autoantibodies
por: Laurynenka, Viktoryia, et al.
Publicado: (2022)

Estrogen Receptor Alpha Signaling Is Responsible for the Female Sex Bias in the Loss of Tolerance and Immune Cell Activation Induced by the Lupus Susceptibility Locus Sle1b
por: Graham, Jared H., et al.
Publicado: (2020)

Monocyte Expressed Macromolecular C1 and C1q Receptors as Molecular Sensors of Danger: Implications in SLE
por: Ghebrehiwet, Berhane, et al.
Publicado: (2014)

cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE
por: Motwani, Mona, et al.
Publicado: (2021)

The First Case Report of Preschool-Onset SS/SLE Coexisting With NMOSD of Chinese Origin
por: Liu, Liqun, et al.
Publicado: (2022)

Self-DNA at the Epicenter of SLE: Immunogenic Forms, Regulation, and Effects
por: Soni, Chetna, et al.
Publicado: (2019)

The effect of prolactin on immune cell subsets involved in SLE pathogenesis
por: Legorreta-Haquet, Maria Victoria, et al.
Publicado: (2022)

Case Report: Response of cutaneous lupus lesions in SLE to interferon receptor blockade parallels reduction of interferon score in blood
por: Günther, Claudia, et al.
Publicado: (2023)

MiRNA Regulation of MIF in SLE and Attenuation of Murine Lupus Nephritis With miR-654
por: Tu, Yang, et al.
Publicado: (2019)

Oxidative Stress in SLE T Cells, Is NRF2 Really the Target to Treat?
por: Ohl, Kim, et al.
Publicado: (2021)

miRNA-Mediated Control of B Cell Responses in Immunity and SLE
por: Schell, Stephanie L., et al.
Publicado: (2021)

A Novel Serum tsRNA for Diagnosis and Prediction of Nephritis in SLE
por: Yang, Ping, et al.
Publicado: (2021)

Signalling via T cell receptor (TCR) in patients with SLE
por: Cebecauer, M, et al.
Publicado: (2001)

The Relationship Between Gene Polymorphism of Leptin and Leptin Receptor and Growth Hormone Deficiency
por: He, Jinshui, et al.
Publicado: (2016)

Sex Hormones and Gender Influence the Expression of Markers of Regulatory T Cells in SLE Patients
por: Singh, Ram P., et al.
Publicado: (2021)

A Novel Gene CDC27 Causes SLE and Is Associated With the Disease Activity
por: Shang, Shunlai, et al.
Publicado: (2022)

Leptin signaling and leptin resistance
por: Liu, Jiarui, et al.
Publicado: (2022)

Leptin Functions in Infectious Diseases
por: Maurya, Radheshyam, et al.
Publicado: (2018)

Pauci-immune Glomerulonephritis in Systemic Lupus Erythematosus (SLE)
por: Liebowitz, Jason, et al.
Publicado: (2018)

Molecular endotypes of type 1 and type 2 SLE
por: Robl, Robert, et al.
Publicado: (2023)

ELISA based assays to measure adenosine deaminases concentration in serum and saliva for the diagnosis of ADA2 deficiency and cancer
por: Luo, Wenwen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dps3cdiqvi035pfnn5541168rq