Kumatakenin inhibited iron-ferroptosis in epithelial cells from colitis mice by regulating the Eno3-IRP1-axis

Inhibition of epithelial ferroptosis in colonic tissues relieved clinical symptoms and improved endoscopic presentations in inflammatory bowel disease (IBD). Kumatakenin, the main ingredient of traditional Chinese medicinal cloves and Alpinia purpurata, is reported to possess therapeutic benefits. H...

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Detalles Bibliográficos
Autores principales: Arenbaoligao, Guo, Xinrui, Xiong, Jiahao, Zhang, Shuangshuang, Yang, Yuewen, Chen, Dapeng, Xie, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063804/
https://www.ncbi.nlm.nih.gov/pubmed/37006994
http://dx.doi.org/10.3389/fphar.2023.1127931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063804/
https://www.ncbi.nlm.nih.gov/pubmed/37006994
http://dx.doi.org/10.3389/fphar.2023.1127931

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