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Skeletal stem/progenitor cells provide the niche for extramedullary hematopoiesis in spleen

In bone marrow, the niche which supports hematopoiesis and nurtures hematopoietic stem cells (HSCs) contains perivascular reticular cells representing a subset of skeletal stem/progenitor cells (SSPCs). These stromal cells which provide the niche are lost or become inadequate during stress, disease...

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Detalles Bibliográficos
Autores principales: O’Neill, Helen C., Lim, Hong Kiat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063897/
https://www.ncbi.nlm.nih.gov/pubmed/37007998
http://dx.doi.org/10.3389/fphys.2023.1148414