Cinobufacini injection suppresses the proliferation of human osteosarcoma cells by inhibiting PIN1-YAP/TAZ signaling pathway

Cinobufacini injection (CI), an aqueous extract of Cutis Bufonis, is clinically used for cancer therapy in China, but its molecular mechanism for the treatment of osteosarcoma (OS) remains unclear. We constructed U2OS ectopic subcutaneous tumor model to verify the anti-OS effect of CI in vivo. Meanw...

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Detalles Bibliográficos
Autores principales: Chen, Yuru, Wang, Yanyan, Zhai, Yu, Yuan, Ye, Wang, Junhong, Jin, Yajing, Dang, Lingling, Song, Liming, Chen, Changbao, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063998/
https://www.ncbi.nlm.nih.gov/pubmed/37006999
http://dx.doi.org/10.3389/fphar.2023.1081363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063998/
https://www.ncbi.nlm.nih.gov/pubmed/37006999
http://dx.doi.org/10.3389/fphar.2023.1081363

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