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4‐octyl itaconate improves the viability of D66H cells by regulating the KEAP1‐NRF2‐GCLC/HO‐1 pathway

As a novel nuclear factor E2‐related factor 2 (NRF2) activator, the itaconate has shown significant therapeutic potential for oxidative stress diseases. However, its role in Vohwinkel syndrome in relation to the gap junction protein beta 2 (GJB2) mutation is still unclear. This study aimed at invest...

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Detalles Bibliográficos
Autores principales: Chen, Yanrui, Wang, Zhenying, Song, Yali, Chen, Nan, Guo, Jing, Liu, Wenmin, Guo, Keying, Ling, Xia, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064036/
https://www.ncbi.nlm.nih.gov/pubmed/36916028
http://dx.doi.org/10.1111/jcmm.17708