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Influence of cyclin D1 splicing variants expression on breast cancer chemoresistance via CDK4/CyclinD1‐pRB‐E2F1 pathway

Cyclin D1 (CCND1), a mediator of cell cycle control, has a G870A polymorphism which results in the formation of two splicing variants: full‐length CCND1 (CCND1a) and C‐terminally truncated CCND1 species (CCND1b). However, the role of CCND1a and CCND1b variants in cancer chemoresistance remains unkno...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhang, Jiaxin, Ma, Qinglong, Zhang, Shasha, Ma, Fengdie, Su, Wei, Zhang, Taotao, Xie, Xiaodong, Di, Cuixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064037/
https://www.ncbi.nlm.nih.gov/pubmed/36915230
http://dx.doi.org/10.1111/jcmm.17716