1400 W, a selective inducible nitric oxide synthase inhibitor, mitigates early neuroinflammation and nitrooxidative stress in diisopropylfluorophosphate-induced short-term neurotoxicity rat model

Organophosphate nerve agent (OPNA) exposure induces acute and long-term neurological deficits. OPNA exposure at sub-lethal concentrations induces irreversible inhibition of acetylcholinesterase and cholinergic toxidrome and develops status epilepticus (SE). Persistent seizures have been associated w...

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Detalles Bibliográficos
Autores principales: Massey, Nyzil, Vasanthi, Suraj Sundara, Samidurai, Manikandan, Gage, Meghan, Rao, Nikhil, Meyer, Christina, Thippeswamy, Thimmasettappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064070/
https://www.ncbi.nlm.nih.gov/pubmed/37008784
http://dx.doi.org/10.3389/fnmol.2023.1125934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064070/
https://www.ncbi.nlm.nih.gov/pubmed/37008784
http://dx.doi.org/10.3389/fnmol.2023.1125934

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