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1400 W, a selective inducible nitric oxide synthase inhibitor, mitigates early neuroinflammation and nitrooxidative stress in diisopropylfluorophosphate-induced short-term neurotoxicity rat model
Organophosphate nerve agent (OPNA) exposure induces acute and long-term neurological deficits. OPNA exposure at sub-lethal concentrations induces irreversible inhibition of acetylcholinesterase and cholinergic toxidrome and develops status epilepticus (SE). Persistent seizures have been associated w...
Autores principales: | Massey, Nyzil, Vasanthi, Suraj Sundara, Samidurai, Manikandan, Gage, Meghan, Rao, Nikhil, Meyer, Christina, Thippeswamy, Thimmasettappa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064070/ https://www.ncbi.nlm.nih.gov/pubmed/37008784 http://dx.doi.org/10.3389/fnmol.2023.1125934 |
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