Investigating the association between fasting insulin, erythrocytosis and HbA1c through Mendelian randomization and observational analyses

BACKGROUND: Insulin resistance (IR) with associated compensatory hyperinsulinemia (HI) are early abnormalities in the etiology of prediabetes (preT2D) and type 2 diabetes (T2D). IR and HI also associate with increased erythrocytosis. Hemoglobin A1c (HbA1c) is commonly used to diagnose and monitor pr...

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Detalles Bibliográficos
Autores principales: Nguyen, Anthony, Khafagy, Rana, Hashemy, Habiba, Kuo, Kevin H. M., Roshandel, Delnaz, Paterson, Andrew D., Dash, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064082/
https://www.ncbi.nlm.nih.gov/pubmed/37008938
http://dx.doi.org/10.3389/fendo.2023.1146099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064082/
https://www.ncbi.nlm.nih.gov/pubmed/37008938
http://dx.doi.org/10.3389/fendo.2023.1146099

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