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High-efficient production of mushroom polyketide compounds in a platform host Aspergillus oryzae

BACKGROUND: Orsellinic acid (2,4-dihydroxy-6-methylbenzoic acid, OA) and its structural analog o-Orsellinaldehyde, have become widely used intermediates in clinical drugs synthesis. Although the research on the biosynthesis of such compounds has made significant progress, due to the lack of suitable...

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Detalles Bibliográficos
Autores principales: Han, Haiyan, Yu, Chunyan, Qi, Jianzhao, Wang, Pengchao, Zhao, Peipei, Gong, Wenbing, Xie, Chunliang, Xia, Xuekui, Liu, Chengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064546/
https://www.ncbi.nlm.nih.gov/pubmed/36998045
http://dx.doi.org/10.1186/s12934-023-02071-9