Allelic phenotype prediction of phenylketonuria based on the machine learning method

BACKGROUND: Phenylketonuria (PKU) is caused by mutations in the phenylalanine hydroxylase (PAH) gene. Our study aimed to predict the phenotype using the allelic genotype. METHODS: A total of 1291 PKU patients with 623 various variants were used as the training dataset for predicting allelic phenotyp...

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Detalles Bibliográficos
Autores principales: Fang, Yang, Gao, Jinshuang, Guo, Yaqing, Li, Xiaole, Yuan, Enwu, Yuan, Erfeng, Song, Liying, Shi, Qianqian, Yu, Haiyang, Zhao, Dehua, Zhang, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064562/
https://www.ncbi.nlm.nih.gov/pubmed/37004080
http://dx.doi.org/10.1186/s40246-023-00481-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064562/
https://www.ncbi.nlm.nih.gov/pubmed/37004080
http://dx.doi.org/10.1186/s40246-023-00481-9

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