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Genome-wide tiled detection of circulating Mycobacterium tuberculosis cell-free DNA using Cas13

Detection of microbial cell-free DNA (cfDNA) circulating in the bloodstream has emerged as a promising new approach for diagnosing infection. Microbial diagnostics based on cfDNA require assays that can detect rare and highly fragmented pathogen nucleic acids. We now report WATSON (Whole-genome Assa...

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Detalles Bibliográficos
Autores principales: Thakku, Sri Gowtham, Lirette, Jackson, Murugesan, Kanagavel, Chen, Julie, Theron, Grant, Banaei, Niaz, Blainey, Paul C., Gomez, James, Wong, Sharon Y., Hung, Deborah T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064635/
https://www.ncbi.nlm.nih.gov/pubmed/37002219
http://dx.doi.org/10.1038/s41467-023-37183-8