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Quantification of mitochondrial cfDNA reveals new perspectives for early diagnosis of colorectal cancer
BACKGROUND: To unravel how the integrity of nuclear and mitochondrial circulating cell-free DNA (cfDNA) contributes to its plasma quantity in colorectal cancer (CRC) patients. METHODS: CfDNA from plasma samples of 80 CRC patients stratified by tumour stage and 50 healthy individuals were extracted....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064655/ https://www.ncbi.nlm.nih.gov/pubmed/36997875 http://dx.doi.org/10.1186/s12885-023-10748-y |