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Quantification of mitochondrial cfDNA reveals new perspectives for early diagnosis of colorectal cancer

BACKGROUND: To unravel how the integrity of nuclear and mitochondrial circulating cell-free DNA (cfDNA) contributes to its plasma quantity in colorectal cancer (CRC) patients. METHODS: CfDNA from plasma samples of 80 CRC patients stratified by tumour stage and 50 healthy individuals were extracted....

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Detalles Bibliográficos
Autores principales: Linke, Christian, Hunger, Richard, Reinwald, Mark, Deckert, Markus, Mantke, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064655/
https://www.ncbi.nlm.nih.gov/pubmed/36997875
http://dx.doi.org/10.1186/s12885-023-10748-y